Clinical Studies on Human Capillaries (I)

Studies on Blood Capillaries

The pathway by which intravenously injected ferritin molecules move from the blood plasma across the capillary wall has been investigated in the muscle of the rat diaphragm. At 2 min after administration, the ferritin molecules are evenly distributed in high concentration in the blood plasma of capillaries and occur within vesicles along the blood front of the endothelium. At the 10-min time po...

Studies on the Permeability of Lymphatic Capillaries

The passageway for interstitial fluids and large molecules across the connective tissue lymph interface has been investigated in dermal lymphatic capillaries in the ears of guinea pigs. Numerous endothelial cells overlap extensively at their margins and lack adhesion devices at many points. The observations suggest that these sites are free to move as a result of slight pressure changes. Immedi...

Vincaleukoblastine. I. Preliminary clinical studies.

The results of therapy with vincaleukoblastine in ~7 pat ients afflicted with various mal ignant diseases have been discussed. The drug caused a marked fall in the leukocyte count, with slight and transient decrease in platelets. A decrease in organ size and tumor mass was often produced. While slight anorexia, nausea, and nervousness have been noted in some patients and epilation or fever in a...

Hemoglobin Yakina. I. Clinical and biochemical studies.

Three members of a family who have erythrocytosis and a new hemoglobin, designated hemoglobin Yakima, are described. The abnormal hemoglobin is characterized by the substitution of histidine for aspartic acid at residue 99 in the beta-chain. Of three possible structure-function relations which would account for the increased oxygen affinity of hemoglobin Yakima, only two seem likely. These are:...

Human T-lymphotropic Virus Type I (HTLV-I) Proviral Load and Clinical Features in Iranian HAM/TSP Patients